Detalhe da pesquisa
1.
Macromolecular condensation organizes nucleolar sub-phases to set up a pH gradient.
Cell
; 187(8): 1889-1906.e24, 2024 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38503281
2.
A disordered region controls cBAF activity via condensation and partner recruitment.
Cell
; 186(22): 4936-4955.e26, 2023 10 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37788668
3.
Sequence grammar underlying the unfolding and phase separation of globular proteins.
Mol Cell
; 82(17): 3193-3208.e8, 2022 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35853451
4.
Competing interactions give rise to two-state behavior and switch-like transitions in charge-rich intrinsically disordered proteins.
Proc Natl Acad Sci U S A
; 119(19): e2200559119, 2022 05 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35512095
5.
Connecting sequence features within the disordered C-terminal linker of Bacillus subtilis FtsZ to functions and bacterial cell division.
Proc Natl Acad Sci U S A
; 119(42): e2211178119, 2022 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36215496
6.
Ligand effects on phase separation of multivalent macromolecules.
Proc Natl Acad Sci U S A
; 118(10)2021 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33653957
7.
PED in 2021: a major update of the protein ensemble database for intrinsically disordered proteins.
Nucleic Acids Res
; 49(D1): D404-D411, 2021 01 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33305318
8.
Decoupling of size and shape fluctuations in heteropolymeric sequences reconciles discrepancies in SAXS vs. FRET measurements.
Proc Natl Acad Sci U S A
; 114(31): E6342-E6351, 2017 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28716919
9.
Profilin reduces aggregation and phase separation of huntingtin N-terminal fragments by preferentially binding to soluble monomers and oligomers.
J Biol Chem
; 293(10): 3734-3746, 2018 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29358329
10.
Monomeric Huntingtin Exon 1 Has Similar Overall Structural Features for Wild-Type and Pathological Polyglutamine Lengths.
J Am Chem Soc
; 139(41): 14456-14469, 2017 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28937758
11.
Overexpression of Q-rich prion-like proteins suppresses polyQ cytotoxicity and alters the polyQ interactome.
Proc Natl Acad Sci U S A
; 111(51): 18219-24, 2014 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25489109
12.
Unmasking the roles of N- and C-terminal flanking sequences from exon 1 of huntingtin as modulators of polyglutamine aggregation.
Proc Natl Acad Sci U S A
; 110(50): 20075-80, 2013 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24282292
13.
CAMELOT: A machine learning approach for coarse-grained simulations of aggregation of block-copolymeric protein sequences.
J Chem Phys
; 143(24): 243123, 2015 Dec 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-26723608
14.
A coarse-grained model for polyglutamine aggregation modulated by amphipathic flanking sequences.
Biophys J
; 107(5): 1226-1235, 2014 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-25185558
15.
Emergent microenvironments of nucleoli.
Nucleus
; 15(1): 2319957, 2024 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-38443761
16.
Metastable condensates suppress conversion to amyloid fibrils.
bioRxiv
; 2024 Mar 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38464104
17.
SOURSOP: A Python package for the analysis of simulations of intrinsically disordered proteins.
bioRxiv
; 2023 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36824878
18.
SOURSOP: A Python Package for the Analysis of Simulations of Intrinsically Disordered Proteins.
J Chem Theory Comput
; 19(16): 5609-5620, 2023 Aug 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37463458
19.
Dynamical control enables the formation of demixed biomolecular condensates.
bioRxiv
; 2023 Jan 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36711465
20.
Dynamical control enables the formation of demixed biomolecular condensates.
Res Sq
; 2023 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36798397